Diisopropylamine → 4-[2-(2-Bromo-5-methoxyphenyl)-1-methylethyl]benzoic acid

HRID 191803Notes

Reaction equation

HRID 191803 reaction equation
[Br:24][c:25]1[c:26]([CH2:33][Br:34])[cH:27][c:28]([O:31][CH3:32])[cH:29][cH:30]1.[CH2:13]([CH3:14])[c:15]1[cH:16][cH:17][c:18]([C:19](=[O:20])[OH:21])[cH:22][cH:23]1.[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH:6]([NH:7][CH:8]([CH3:9])[CH3:10])([CH3:11])[CH3:12]>>[CH:13]([CH3:14])([c:15]1[cH:16][cH:17][c:18]([C:19](=[O:20])[OH:21])[cH:22][cH:23]1)[CH2:33][c:26]1[c:25]([Br:24])[cH:30][cH:29][c:28]([O:31][CH3:32])[cH:27]1

Participants

6

Reactant 5

HCID 7912DiisopropylamineHCID 8028TetrahydrofuranHCID 120864-Ethylbenzoic AcidHCID 35259512-Bromo-5-methoxybenzyl bromideHCID 178418339Butyllithium

Product 1

HCID 674857104-[2-(2-Bromo-5-methoxyphenyl)-1-methylethyl]benzoic acid

Sources & evidence

ORD record
ord-6af895e569f84364a8e3c3f7d85a7582
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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