HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Malic Acid → Sunitinib Malate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Malic Acid | HCID 222656 | — |
| Reactant | Sunitinib | HCID 5329102 | — |
| Solvent | Butyl Acetate | HCID 31272 | — |
| Product | Sunitinib Malate | HCID 6456015 | — |
Reaction Steps
Sunitinib base (300 mg), L-malic acid (101 mg) and butyl acetate (10 ml) were heated to reflux 10 min. The suspension was allowed to cool to RT, filtered, washed with n-hexane and dried on air.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08618309B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-140a84110053429bad95108b962e12b4 |
| Source note | uspto-grants-2013_12 |