Isopropyl iodide → 9H-Fluorene, 9-(1-methylethyl)-

HRID 1918426Notes

Reaction equation

HRID 1918426 reaction equation
[CH:1]1[C:13]2[CH2:12][C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]=[CH:3][CH:2]=1.[Li][CH2:15][CH2:16][CH2:17]C.IC(C)C.OC1O[C@@H](CO)[C@H](O)[C@H](O)[C@H]1O>>[CH:16]([CH:12]1[C:11]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[C:5]2[C:13]1=[CH:1][CH:2]=[CH:3][CH:4]=2)([CH3:17])[CH3:15]

Participants

5

Reactant 4

HCID 6362Isopropyl iodideHCID 6853FluoreneHCID 10219674L-AltroseHCID 178418339Butyllithium

Product 1

HCID 186969H-Fluorene, 9-(1-methylethyl)-

Procedure

Fluorene (15.0 g, 90.4 mmol), n-BuLi (48.1 ml, 120 mmol, 2.5 M in hexane), RX=2-iodopropane (14.0 ml, 139.6 mmol). 42 was isolated as a yellowish solid (18.7 g, quant.). The analytical data were identical with these to be found in the literature (M. A. Schmidt, H. G. Alt, W. Milius, J. Organomet. Chem. 1996, 525, 15).

Workup

  1. custom42 was isolated as a yellowish solid (18.7 g, quant.)

Sources & evidence

ORD record
ord-7e148871503b46838dc84cee25182137
Source dataset
uspto-grants-2013_12
Patent number
US08618328B2

Reaction notes

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