Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 3-Chloroaniline | HCID 7932 | — |
| Reactant | HCID 57500684 | HCID 57500684 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | HCID 57500685 | HCID 57500685 | — |
Reaction Steps
5-chloropyrido[4,3-c][1,7]naphthyridine (10 mg) was mixed in NMP (0.3 ml) with 3-chloroaniline (60 ul) and the mixture was heated at 120° C. for 10 min. Water was added and the resulting solid was filtered and dried. N-(3-chlorophenyl)pyrido[4,3-c][1,7]naphthyridin-5-amine was isolated as a solid (5 mg). LCMS (ES)>95% pure, m/z 307 [M+1]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08168651B2 |
|---|
| Source dataset | uspto-grants-2012_05 |
|---|
| ORD ID | ord-e340a6259ca541109f1e2b5425a2f606 |
|---|
| Source note | uspto-grants-2012_05 |
|---|
