Cyclopentanol → HCID 67500259, compound

HRID 1919824Notes

Reaction equation

HRID 1919824 reaction equation
F[C:2](F)(F)[CH2:3][O:4][C:5]1[N:10]=[CH:9][C:8]([CH:11]([NH2:13])[CH3:12])=[CH:7][CH:6]=1.ClC1C=C[C:20]([C:21]#N)=[CH:19]N=1.C1(O)CCCC1>>[CH:3]1([O:4][C:5]2[N:10]=[CH:9][C:8]([CH:11]([NH2:13])[CH3:12])=[CH:7][CH:6]=2)[CH2:21][CH2:20][CH2:19][CH2:2]1

Participants

4

Reactant 3

HCID 7298CyclopentanolHCID 51520946-Chloro-3-pyridinecarbonitrileHCID 586291003-Pyridinemethanamine, alpha-methyl-6-(2,2,2-trifluoroethoxy)-

Product 1

HCID 67500259HCID 67500259, compound

Procedure

The title compound was synthesised according to the 2-step procedure described for the synthesis of 1-[6-(2,2,2-trifluoroethoxy)pyridin-3-yl]ethanamine starting from 6-chloronicotinonitrile and cyclopentanol.

Sources & evidence

ORD record
ord-9756df6c967e40209e13d204abac773a
Source dataset
uspto-grants-2012_05
Patent number
US08168668B2

Reaction notes

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