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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1919828Generated: October 27, 2026

4-Fluoro-3-(trifluoromethyl)benzonitrile → HCID 67500530, compound

https://huagongshe.com/reaction/1919828

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-3-(trifluoromethyl)benzonitrileHCID 144255—
Reactant2-Methoxy-1-propanol, (2S)-HCID 642402—
ReactantHCID 67500773HCID 67500773—
ProductHCID 67500530HCID 67500530—

Reaction Steps

The title compound was synthesized according to the procedure described for the synthesis of 1-[4-[(1-methylpiperidin-4-yl)oxy]-3-(trifluoromethyl)phenyl]ethanamine, part A and B, starting from 4-fluoro-3-(trifluoromethyl)benzonitrile and (S)-(+)-2-methoxypropanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08168668B2
Source datasetuspto-grants-2012_05
ORD IDord-0e0a06b79df942febf149935a4ee60f1
Source noteuspto-grants-2012_05