Pyrrolidine → 2-(5-Fluoro-2-methyl-3-(2-(pyrrolidin-1-ylsulfonyl)benzyl)-1H-indol-1-yl)acetic Acid

HRID 1919859Notes

Reaction equation

HRID 1919859 reaction equation
N1CCCC1.[F:6][C:7]1[CH:8]=[C:9]2[C:13](=[CH:14][CH:15]=1)[N:12]([CH2:16][C:17]([OH:19])=[O:18])[C:11]([CH3:20])=[C:10]2[CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=1[S:28]([N:31]1[CH2:36]C[CH2:34][CH2:33][CH2:32]1)(=[O:30])=[O:29]>>[F:6][C:7]1[CH:8]=[C:9]2[C:13](=[CH:14][CH:15]=1)[N:12]([CH2:16][C:17]([OH:19])=[O:18])[C:11]([CH3:20])=[C:10]2[CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=1[S:28]([N:31]1[CH2:36][CH2:34][CH2:33][CH2:32]1)(=[O:30])=[O:29]

Participants

3

Reactant 2

HCID 31268PyrrolidineHCID 671595512-(5-fluoro-2-methyl-3-(2-(piperidin-1-ylsulfonyl)benzyl)-1H-indol-1-yl)acetic acid

Product 1

HCID 441968792-(5-Fluoro-2-methyl-3-(2-(pyrrolidin-1-ylsulfonyl)benzyl)-1H-indol-1-yl)acetic Acid

Procedure

Pyrrolidine was used as starting material in Procedure Q, otherwise this compound was prepared in a similar manner to Compound 2, using Procedures N, P, Q & L.

Sources & evidence

ORD record
ord-76ca00852dd24e52a508e54a9ecfd4fd
Source dataset
uspto-grants-2012_05
Patent number
US08168673B2

Reaction notes

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