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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 191996Generated: October 30, 2026

Tetrahydrofuran → 3-Cyclopentyl-1-(2,6-dimethylphenyl)-5-oxo-pyrrolidine-3-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide

https://huagongshe.com/reaction/191996

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantBenzenamine, 3,5-bis(trifluoromethyl)-HCID 9480—
Reactant3-Cyclopentyl-1-(2,6-dimethylphenyl)-5-oxo-pyrrolidine-3-carboxylic acid methyl esterHCID 58218803—
ReactantButyllithiumHCID 178418339—
Product3-Cyclopentyl-1-(2,6-dimethylphenyl)-5-oxo-pyrrolidine-3-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amideHCID 51033903—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-23a5293ccded4ec2bd5d25f176e87c73
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)