Cyclopropanecarbonyl chloride → HCID 66605234, compound

HRID 1920001Notes

Reaction equation

[CH2:1]([O:3][C:4](=[O:26])[CH2:5][C:6]1[CH:7]=[C:8]([C:12]2[CH:17]=[CH:16][C:15]([C:18]([F:21])([F:20])[F:19])=[CH:14][C:13]=2[CH2:22][NH:23][CH2:24][CH3:25])[CH:9]=[CH:10][CH:11]=1)[CH3:2].[CH:27]1([C:30](Cl)=[O:31])[CH2:29][CH2:28]1>>[CH2:1]([O:3][C:4](=[O:26])[CH2:5][C:6]1[CH:7]=[C:8]([C:12]2[CH:17]=[CH:16][C:15]([C:18]([F:19])([F:20])[F:21])=[CH:14][C:13]=2[CH2:22][N:23]([C:30]([CH:27]2[CH2:29][CH2:28]2)=[O:31])[CH2:24][CH3:25])[CH:9]=[CH:10][CH:11]=1)[CH3:2]

Participants

Reactant 2

HCID 77637Cyclopropanecarbonyl chloride

HCID 66604210HCID 66604210, compound

Product 1

HCID 66605234HCID 66605234, compound

Procedure

Prepared according to the procedure described in Example 1, Step 6, using the following starting materials: (2′-ethylaminomethyl-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid ethyl ester and cyclopropanecarbonyl chloride.

Workup

customPrepared

Sources & evidence

ORD record: ord-22d246d0373748a78d0b1776e898160a
Source dataset: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08168678B2

Reaction notes

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