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HRID1920316

反应详情

EQUATION

反应方程式

HRID 1920316 的结构方程式

REACTANTS

反应物

2
结构：NS(=O)(=O)c1ccc(F)c(S(=O)(=O)C(F)(F)F)c1
HCID25058452

4-Fluoro-3-(trifluoromethanesulfonyl)benzene-1-sulfonamide

C7H5F4NO4S2

结构：N[C@H](CCN1CCOCC1)CSc1ccccc1
HCID25058453

(2R)-4-(Morpholin-4-yl)-1-(phenylsulfanyl)butan-2-amine

C14H22N2OS

PRODUCTS

生成物

1
结构：NS(=O)(=O)c1ccc(N[C@H](CCN2CCOCC2)CSc2ccccc2)c(S(=O)(=O)C(F)(F)F)c1
HCID25058454

4-{[(2R)-4-(Morpholin-4-yl)-1-(phenylsulfanyl)butan-2-yl]amino}-3-(trifluoromethanesulfonyl)benzene-1-sulfonamide

C21H26F3N3O5S3

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCN(CC)CC
溶剂HCID8471

Triethylamine

C6H15N

PROCEDURE

实验过程

reacting 4-fluoro-3-((trifluoromethyl)sulfonyl)benzenesulfonamide, (1R)-3-morpholin-4-yl-1-((phenylthio)methyl)propylamine and triethylamine to provide 4-(((1R)-3-morpholin-4-yl-1-((phenylthio)methyl)propyl)amino)-3-((trifluoromethyl)sulfonyl)benzenesulfonamide and isolating or not isolating the 4-(((1R)-3-morpholin-4-yl-1-((phenylthio)methyl)propyl)amino)-3-((trifluoromethyl)sulfonyl)benzenesulfonamide; and