Diisopropylethylamine → 2-(Diethoxymethyl)-4,4-dimethylcyclohexanone

HRID 1920367Notes

Reaction equation

HRID 1920367 reaction equation
[CH3:1][C:2]1([CH3:9])[CH2:7][CH2:6][C:5](=[O:8])[CH2:4][CH2:3]1.F[B-](F)(F)F.[CH2:15]([O:17][CH+:18][O:19][CH2:20][CH3:21])[CH3:16].C(N(CC)C(C)C)(C)C>>[CH2:15]([O:17][CH:18]([O:19][CH2:20][CH3:21])[CH:4]1[CH2:3][C:2]([CH3:9])([CH3:1])[CH2:7][CH2:6][C:5]1=[O:8])[CH3:16]

Participants

4

Reactant 3

HCID 81531DiisopropylethylamineHCID 138166Cyclohexanone, 4,4-dimethyl-HCID 178468207HCID 178468207, compound

Product 1

HCID 580183412-(Diethoxymethyl)-4,4-dimethylcyclohexanone

Procedure

reacting 4,4-dimethylcyclohexanone, diethoxycarbenium fluoroborate and N,N-diisopropylethylamine at about −60° C. to −90° C. to provide (2-(diethoxymethyl)-4,4-dimethylcyclohexanone and isolating or not isolating the 2-(diethoxymethyl)-4,4-dimethylcyclohexanone;

Workup

  1. customat about −60° C. to −90° C.

Sources & evidence

ORD record
ord-3b244d8fbb2a429e83cfe29f9ac4af9d
Source dataset
uspto-grants-2012_05
Patent number
US08168784B2

Reaction notes

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