Dichloromethane → HCID 86643443, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 3-isobutyl glutaric anhydride (5 grams) in dichloromethane (10 ml), added diethyl amine (4.3 grams) and stirred the reaction mixture for 12 hrs at 25° C. The reaction mixture was quenched with water (10 ml) and the pH of the reaction mixture adjusted to 1.0 using hydrochloric acid. The organic layer was separated and the aqueous layer was extracted with dichloromethane. The organic layers were combined and the solvent distilled off to provide the title compound as a residue.

Provenance & Evidence