Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1920607Generated: October 28, 2026

Citric Acid → HCID 131729695, compound

https://huagongshe.com/reaction/1920607

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCitric AcidHCID 311—
ReactantGlycolideHCID 65432—
ReactantHCID 5487480HCID 5487480—
SolventWaterHCID 962—
SolventN-methyl-2-pyrrolidoneHCID 13387—
ProductHCID 131729695HCID 131729695—

Reaction Steps

The following composition was prepared. The polymer solution was composed of 50% by weight of poly(lactide-co-glycolide) (PLGH) with a lactide to glycolide ratio of 75/25 and with an inherent viscosity of 0.20 dL/g dissolved in 50% by weight N-methyl-2-pyrrolidone. The active portion was composed of GHRP-1 and citric acid. The ratio of citric acid to GHRP-1 was about 1.25:1 on a molar basis. The GHRP-1 was dissolved in water; citric acid was added to dissolve; and the solution was filled into a syringe and lyophilized. The contents of the completed syringe were about 80 mg of GHRP-1 and about 20 mg of citric acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08173148B2
Source datasetuspto-grants-2012_05
ORD IDord-022caf25e136418bbb516df466b19be9
Source noteuspto-grants-2012_05