Dichloromethane → Methyl 3-(3-aminopiperidin-1-yl)benzoate

HRID 192070Notes

Reaction equation

HRID 192070 reaction equation
[C:8]([O:9][C:10](=[O:11])[NH:15][CH:16]1[CH2:17][N:18]([c:22]2[cH:23][c:24]([C:25](=[O:26])[O:27][CH3:28])[cH:29][cH:30][cH:31]2)[CH2:19][CH2:20][CH2:21]1)([CH3:12])([CH3:13])[CH3:14].[Cl:32][CH2:33][Cl:34].[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[NH2:15][CH:16]1[CH2:17][N:18]([c:22]2[cH:23][c:24]([C:25](=[O:26])[O:27][CH3:28])[cH:29][cH:30][cH:31]2)[CH2:19][CH2:20][CH2:21]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 58992690Methyl 3-[3-(tert-butoxycarbonylamino)piperidin-1-yl]benzoate

Product 1

HCID 58992611Methyl 3-(3-aminopiperidin-1-yl)benzoate

Sources & evidence

ORD record
ord-98ea8a60b13c4c2da49ba64c3aad0554
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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