Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1920703Generated: November 1, 2026

HCID 54123383, compound → HCID 46941063, compound

https://huagongshe.com/reaction/1920703

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 54123383HCID 54123383—
ReactantHCID 59526816HCID 59526816—
ReactantHCID 86646221HCID 86646221—
ProductHCID 46941063HCID 46941063—

Reaction Steps

The title compound is prepared from (R)-2-(pyrrolidin-3-yl)propan-2-amine (Fedji, et al., 1994) and 9-cyclopropyl-7-fluoro-3-hydroxyl-8-methoxy-4-oxo-4,9-dihydrothieno[2,3-b]quinoline-2-carbonitrile using the method described above for the preparation of 9-cyclopropyl-6-fluoro-7-((R)-3-(S)-1-(2-fluoroethylamino)ethyl)pyrrolidin-1-yl)-3-hydroxyl-8-methoxy-4-oxo-4,9-dihydrothieno[2,3-b]quinoline-2-carbonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08173636B2
Source datasetuspto-grants-2012_05
ORD IDord-0dd60fa0e4d642aa9ab1e3fed7baa42d
Source noteuspto-grants-2012_05