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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1920822Generated: November 1, 2026

HCID 10877054, compound → HCID 59198402, compound

https://huagongshe.com/reaction/1920822

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 10877054HCID 10877054—
ReactantHCID 55136146HCID 55136146—
SolventTolueneHCID 1140—
ProductHCID 59198402HCID 59198402—

Reaction Conditions

Temperature80 °C

Reaction Steps

A mixture of N-(5-cyanopyridin-2-yl)pivalamide (1.22 g, 6.00 mmol) and MeAl(Cl)NH2 (18 mL, 0.67M solution in toluene, 12.00 mmol) in 25 mL toluene is heated at 80° C. for 15 hours. The resulting N-(5-carbamimidoylpyridin-2-yl)pivalamide is used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08173647B2
Source datasetuspto-grants-2012_05
ORD IDord-3833d5d80f9549c98f742202919d6417
Source noteuspto-grants-2012_05