反应详情

温度

160 °C

A mixture of ethyl 4-aminobenzoate (1.00 g, 6.05 mmol) and 2-fluoronitrobenzene (0.64 mL, 6.05 mmol) was heated at 160° C. for 18 h. The crude product was purified by silica gel chromatography, eluting with hexane:EtOAc—70:30, to give the title compound. MS: m/z=287 (M+1).

1. customThe crude product was purified by silica gel chromatography
2. washeluting with hexane