2-Morpholin-4-yl-2-(3-pyridyl)ethylamine → HCID 67492336, compound

Participants

Reaction Steps

5-(5-Ethyl-2-methyl-6-oxo-1,6-dihydropyridin-3-yl)thiophene-2-sulfonyl chloride is reacted with 2-(morpholin-4-yl)-2-(pyridin-3-yl)ethylamine as described in Steps 5 and 6, Example 24 to give the title compound as a white solid (55% yield). LC/MS: RT 2.06 min; m/e 489; 1H NMR (δ, ppm): 11.85 (1H, br), 8.98 (1H, s), 8.86 (1H, d), 8.54 (1H, d), 7.90 (2H, t), 7.58 (1H, t), 7.34 (1H, s), 7.1.7 (1H, d), 4.65 (1H, br), 3.6-4.10 (8H, br), 2.8-3.1 (2H, br), 2.40 (2H, q), 2.33 (3H, s), 1.10 (3H, t).

Provenance & Evidence