Piperazine → HCID 67492426, compound

Participants

Reaction Steps

5-(5-Ethyl-2-methyl-6-oxo-1,6-dihydropyridin-3-yl)thiophene-2-sulfonyl chloride is reacted with piperazine as described in Steps 5 and 6, Example 24 to give the title compound as a solid (73.3% yield). LC/MS: RT 2.07 min; m/e 368 (M+H); 1H NMR (δ, ppm): 11.8 (1H, br s), 9.5 (1H, s), 7.65 (1H, d); 7.35 (1H, s); 7.3 (1H, d), 3.2 (8H, m), 2.4 (2H, q), 2.36 (3H, s), 1.1 (3H, t).

Provenance & Evidence