HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(3,3-Difluoropyrrolidin-1-yl)ethan-1-amine → HCID 58808606, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(3,3-Difluoropyrrolidin-1-yl)ethan-1-amine | HCID 53403552 | — |
| Reactant | 5-(5-Ethyl-2-methyl-6-oxo-1,6-dihydropyridin-3-yl)thiophene-2-sulfonyl chloride | HCID 86610352 | — |
| Product | HCID 58808606 | HCID 58808606 | 43% |
Reaction Steps
5-(5-Ethyl-2-methyl-6-oxo-1,6-dihydropyridin-3-yl)thiophene-2-sulfonyl chloride is reacted with 2-(3,3-difluoro-pyrrolidin-1-yl)-ethylamine as described in Step 5, Example 24 to give the title compound (43% yield). LC/MS: RT 1.32 min; m/e 432 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08173682B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-fc3cc13f187e4707a56189b5be66ea2b |
| Source note | uspto-grants-2012_05 |