Piperidin-4-ol → HCID 58808552, compound

HRID 1921470Notes

Reaction equation

HRID 1921470 reaction equation
[CH2:1]([C:3]1[C:8](=[O:9])[NH:7][C:6]([CH3:10])=[C:5]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([CH:17]=O)[N:12]=2)[CH:4]=1)[CH3:2].[OH:19][CH:20]1[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]1>>[CH2:1]([C:3]1[C:8](=[O:9])[NH:7][C:6]([CH3:10])=[C:5]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([CH2:17][N:23]3[CH2:24][CH2:25][CH:20]([OH:19])[CH2:21][CH2:22]3)[N:12]=2)[CH:4]=1)[CH3:2]

Participants

3

Reactant 2

HCID 79341Piperidin-4-olHCID 58808670HCID 58808670, compound

Product 1

HCID 58808552HCID 58808552, compound

Procedure

5′-Ethyl-2′-methyl-6′-oxo-1′,6′-dihydro-[2,3′]bipyridinyl-6-carbaldehyde prepared in accordance with PREPARATION 11 is reacted with 4-hydroxypiperidine as described in Method A, Example 123 to give the title compound. MS: m/e=328 (M+H).

Sources & evidence

ORD record
ord-8a9b1df2f6694268aeb25765aa5a452f
Source dataset
uspto-grants-2012_05
Patent number
US08173682B2

Reaction notes

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