Pyrrolidine → HCID 58808624, compound

HRID 1921483Notes

Reaction equation

HRID 1921483 reaction equation
[CH2:1]([C:3]1[C:8](=[O:9])[NH:7][C:6]([CH3:10])=[C:5]([C:11]2[CH:16]=[CH:15][C:14]([C:17]([OH:19])=O)=[CH:13][N:12]=2)[CH:4]=1)[CH3:2].[NH:20]1[CH2:24][CH2:23][CH2:22][CH2:21]1>>[CH2:1]([C:3]1[C:8](=[O:9])[NH:7][C:6]([CH3:10])=[C:5]([C:11]2[CH:16]=[CH:15][C:14]([C:17]([N:20]3[CH2:24][CH2:23][CH2:22][CH2:21]3)=[O:19])=[CH:13][N:12]=2)[CH:4]=1)[CH3:2]

Participants

3

Reactant 2

HCID 31268PyrrolidineHCID 58808553HCID 58808553, compound

Product 1

HCID 58808624HCID 58808624, compound

Procedure

Method 1, Example 205 is substantially repeated except for utilizing 5′-ethyl-2′-methyl-6′-oxo-1′,6′-dihydro-[2,3′]bipyridinyl-5-carboxylic acid and pyrrolidine to afford the title compound. MS: m/e=312 (M+H).

Sources & evidence

ORD record
ord-b37352e21df7472896d244e4065f57b8
Source dataset
uspto-grants-2012_05
Patent number
US08173682B2

Reaction notes

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