1-Amino-2-propanol → HCID 71110904, compound

HRID 1921499Notes

Reaction equation

HRID 1921499 reaction equation
[CH2:1]([C:3]1[C:8](=[O:9])[NH:7][C:6]([CH3:10])=[C:5]([C:11]2[CH:12]=[N:13][CH:14]=[C:15]([C:17]([OH:19])=O)[CH:16]=2)[CH:4]=1)[CH3:2].[OH:20][CH:21]([CH3:24])[CH2:22][NH2:23]>>[OH:20][CH:21]([CH3:24])[CH2:22][NH:23][C:17]([C:15]1[CH:16]=[C:11]([C:5]2[CH:4]=[C:3]([CH2:1][CH3:2])[C:8](=[O:9])[NH:7][C:6]=2[CH3:10])[CH:12]=[N:13][CH:14]=1)=[O:19]

Participants

3

Reactant 2

HCID 41-Amino-2-propanolHCID 588087025'-Ethyl-2'-methyl-6'-oxo-1',6'-dihydro-[3,3']bipyridinyl-5-carboxylic acid

Product 1

HCID 71110904HCID 71110904, compound

Procedure

Method 1, Example 205 is substantially repeated except for utilizing 5′-ethyl-2′-methyl-6′-oxo-1′,6′-dihydro-[3,3′]bipyridinyl-5-carboxylic acid and 2-hydroxy-propylamine to afford the title compound. MS: m/e=316 (M+H).

Sources & evidence

ORD record
ord-1a484481f0a14cc3a53bc8cae282173c
Source dataset
uspto-grants-2012_05
Patent number
US08173682B2

Reaction notes

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