4-Piperidone → HCID 58808531, compound

HRID 1921504Notes

Reaction equation

HRID 1921504 reaction equation
[CH2:1]([C:3]1[C:8](=[O:9])[NH:7][C:6]([CH3:10])=[C:5]([C:11]2[CH:12]=[N:13][CH:14]=[C:15]([C:17]([OH:19])=O)[CH:16]=2)[CH:4]=1)[CH3:2].[O:20]=[C:21]1[CH2:26][CH2:25][NH:24][CH2:23][CH2:22]1>>[CH2:1]([C:3]1[C:8](=[O:9])[NH:7][C:6]([CH3:10])=[C:5]([C:11]2[CH:12]=[N:13][CH:14]=[C:15]([C:17]([N:24]3[CH2:25][CH2:26][C:21](=[O:20])[CH2:22][CH2:23]3)=[O:19])[CH:16]=2)[CH:4]=1)[CH3:2]

Participants

3

Reactant 2

HCID 337214-PiperidoneHCID 588087025'-Ethyl-2'-methyl-6'-oxo-1',6'-dihydro-[3,3']bipyridinyl-5-carboxylic acid

Product 1

HCID 58808531HCID 58808531, compound

Procedure

Method 1, Example 205 is substantially repeated except for utilizing 5′-ethyl-2′-methyl-6′-oxo-1′,6′-dihydro-[3,3′]bipyridinyl-5-carboxylic acid and 4-oxo-piperidine to afford the title compound. MS: m/e=340 (M+H).

Sources & evidence

ORD record
ord-384ec080da554307bbc4c9602c793b1f
Source dataset
uspto-grants-2012_05
Patent number
US08173682B2

Reaction notes

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