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Mafenide → 5'-Ethyl-2'-methyl-6'-oxo-1',6'-dihydro-[3,3']bipyridinyl-5-carboxylic acid 4-sulfamoyl-benzylamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Mafenide | HCID 3998 | — |
| 反応物 | 5'-Ethyl-2'-methyl-6'-oxo-1',6'-dihydro-[3,3']bipyridinyl-5-carboxylic acid | HCID 58808702 | — |
| 生成物 | 5'-Ethyl-2'-methyl-6'-oxo-1',6'-dihydro-[3,3']bipyridinyl-5-carboxylic acid 4-sulfamoyl-benzylamide | HCID 58808639 | — |
反応手順
Method 1, Example 205 is substantially repeated except for utilizing 5′-ethyl-2′-methyl-6′-oxo-1′,6′-dihydro-[3,3′]bipyridinyl-5-carboxylic acid and 4-sulfamoyl-benzyl-amine to afford the title compound. MS: m/e=427 (M+H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08173682B2 |
| 出典データセット | uspto-grants-2012_05 |
| ORD ID | ord-b17fa4edb307450781c07f7d80fb4c3e |
| 出典メモ | uspto-grants-2012_05 |