N,O-Dimethylhydroxylamine → HCID 58808530, compound

HRID 1921543Notes

Reaction equation

HRID 1921543 reaction equation
[CH2:1]([C:3]1[C:8](=[O:9])[NH:7][C:6]([CH3:10])=[C:5]([C:11]2[S:15][C:14]([C:16]([OH:18])=O)=[CH:13][CH:12]=2)[CH:4]=1)[CH3:2].[CH3:19][O:20][NH:21][CH3:22]>>[CH3:19][O:20][N:21]([CH3:22])[C:16]([C:14]1[S:15][C:11]([C:5]2[CH:4]=[C:3]([CH2:1][CH3:2])[C:8](=[O:9])[NH:7][C:6]=2[CH3:10])=[CH:12][CH:13]=1)=[O:18]

Participants

3

Reactant 2

HCID 14232N,O-DimethylhydroxylamineHCID 67492337HCID 67492337, compound

Product 1

HCID 58808530HCID 58808530, compoundYield 85%

Procedure

Method 1, Example 205 is substantially repeated except for utilizing 5-(5-ethyl-2-methyl-6-oxo-1,6-dihydro-pyridin-3-yl)-thiophene-2-carboxylic acid and methoxy-methylamine to afford the title compound (85% yield). LC/MS: RT 2.64 min; m/e 307 (M+H).

Sources & evidence

ORD record
ord-f6c93336849e4b0e9430f6a53d951f47
Source dataset
uspto-grants-2012_05
Patent number
US08173682B2

Reaction notes

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