Benzenesulfonyl chloride → HCID 58808656, compound

Participants

Reaction Steps

6-Amino-5′-ethyl-2′-methyl-1′H-[2,3′]bipyridinyl-6′-one (1 molar equivalent), prepared in accordance with the procedures of PREPARATION 12, is dissolved in pyridine (approx. 10 ml/mmol) and, at room temperature, 1.3 molar equivalent of benzene sulfonyl chloride is added, and the reaction mixture is stirred at room temperature for 36 hrs. The solution is completely concentrated and then purified directly by RP-HPLC. MS: m/e=370 (M+H).

Provenance & Evidence