HRID1921881

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCOC(=O)CCCCC(C=O)Cc1cc(F)c(O[Si](C(C)C)(C(C)C)C(C)C)c(F)c1

HCID57971915

未命名化合物

结构：Fc1ccc(OCc2ccccc2Cl)c(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)c1.[Br-]

HCID86634289

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)CCCCC(C=Cc1cc(F)ccc1OCc1ccccc1Cl)Cc1cc(F)c(O[Si](C(C)C)(C(C)C)C(C)C)c(F)c1

HCID67493002

未命名化合物

PROCEDURE

实验过程

Reaction in analogy to Example 21A of [2-(2-chlorobenzyloxy)-5-fluorobenzyl]tri-phenylphosphonium bromide and ethyl 7-(3,5-difluoro-4-triisopropylsilanyloxyphenyl)-6-formylheptanoate results in the title compound with 70% of theory as E/Z mixture (2:1).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-e5e760b0d74a4debb2d4a5e744353f82
来源数据集: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08173704B2
来源说明: uspto-grants-2012_05

反应 SMILES

[Br-].[Cl:2][C:3]1[CH:37]=[CH:36][CH:35]=[CH:34][C:4]=1[CH2:5][O:6][C:7]1[CH:32]=[CH:31][C:30]([F:33])=[CH:29][C:8]=1[CH2:9][P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1.[F:38][C:39]1[CH:40]=[C:41]([CH2:57][CH:58]([CH:68]=O)[CH2:59][CH2:60][CH2:61][CH2:62][C:63]([O:65][CH2:66][CH3:67])=[O:64])[CH:42]=[C:43]([F:56])[C:44]=1[O:45][Si:46]([CH:53]([CH3:55])[CH3:54])([CH:50]([CH3:52])[CH3:51])[CH:47]([CH3:49])[CH3:48]>>[F:38][C:39]1[CH:40]=[C:41]([CH:42]=[C:43]([F:56])[C:44]=1[O:45][Si:46]([CH:47]([CH3:49])[CH3:48])([CH:50]([CH3:52])[CH3:51])[CH:53]([CH3:54])[CH3:55])[CH2:57][CH:58]([CH:68]=[CH:9][C:8]1[CH:29]=[C:30]([F:33])[CH:31]=[CH:32][C:7]=1[O:6][CH2:5][C:4]1[CH:34]=[CH:35][CH:36]=[CH:37][C:3]=1[Cl:2])[CH2:59][CH2:60][CH2:61][CH2:62][C:63]([O:65][CH2:66][CH3:67])=[O:64]