HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 3-oxopyrrolidine-1-carboxylate → 4-(6-methoxy-4-(pyrrolidin-3-ylamino)naphthalen-2-yl)-N-methylpyrimidin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 3-oxopyrrolidine-1-carboxylate | HCID 471360 | — |
| Reactant | 4-(4-amino-6-methoxynaphthalen-2-yl)-N-methylpyrimidin-2-amine | HCID 58336395 | — |
| Product | 4-(6-methoxy-4-(pyrrolidin-3-ylamino)naphthalen-2-yl)-N-methylpyrimidin-2-amine | HCID 58336426 | — |
Reaction Steps
4-(6-methoxy-4-(pyrrolidin-3-ylamino)naphthalen-2-yl)-N-methylpyrimidin-2-amine 148 was synthesized according to General Procedure E utilizing compound 33 and replacing tert-butyl 4-oxopiperidine-1-carboxylate with tert-butyl 3-oxopyrrolidine-1-carboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08173808B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-8c752cd114c14c3ea3dabd7edb7c8f51 |
| Source note | uspto-grants-2012_05 |