HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 178484813, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 178486046 | HCID 178486046 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 178484813 | HCID 178484813 | 51.7% |
Reaction Steps
A solution of cis-4-[{[(1,1-dimethylethyl)oxy]carbonyl}(methyl)amino]cyclohexane carboxylic acid (2.5 g, 16 mmol, 1.0 equiv) and 1 M HCl in dioxane (15 mL) was heated to reflux for 4 h. The solvent was removed under reduced pressure to afford 1.3 g of the title compound. This material was used without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08173805B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-e298bc940c2f4281878aab7fed4d8370 |
| Source note | uspto-grants-2012_05 |