Dichloromethane → N-methyl-2-[1-[[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl]-4-piperidinyl]-N-(1,2,3,4-tetrahydro-1-naphthalenyl)-4-thiazolecarboxamide
Reaction equation
[CH3:13][CH2:14][N:15]([CH2:16][CH3:17])[CH2:18][CH3:19].[CH3:1][NH:2][CH:3]1[CH2:4][CH2:5][CH2:6][c:7]2[cH:8][cH:9][cH:10][cH:11][c:12]21.[CH3:20][c:21]1[cH:22][c:23]([C:43]([F:44])([F:45])[F:46])[n:24][n:25]1[CH2:26][C:27](=[O:28])[N:29]1[CH2:30][CH2:31][CH:32]([c:35]2[s:36][cH:37][c:38]([C:40](=[O:41])[Cl:42])[n:39]2)[CH2:33][CH2:34]1.[Cl:47][CH2:48][Cl:49]>>[CH3:1][N:2]([CH:3]1[CH2:4][CH2:5][CH2:6][c:7]2[cH:8][cH:9][cH:10][cH:11][c:12]21)[C:40]([c:38]1[cH:37][s:36][c:35]([CH:32]2[CH2:31][CH2:30][N:29]([C:27]([CH2:26][n:25]3[c:21]([CH3:20])[cH:22][c:23]([C:43]([F:44])([F:45])[F:46])[n:24]3)=[O:28])[CH2:34][CH2:33]2)[n:39]1)=[O:41]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-5423f249a3d64491b3d3121142873358
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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