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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1922098Generated: October 30, 2026

3-Amino-4-fluorophenol → N-(2-fluoro-5-hydroxyphenyl)-3-oxo-2-(4-pyrazol-1-ylbenzyl)butyramide

https://huagongshe.com/reaction/1922098

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Amino-4-fluorophenolHCID 13519180—
Reactant3-oxo-2-(4-pyrazol-1-ylbenzyl)thiobutyric acid S-tert-butyl esterHCID 86642372—
ProductN-(2-fluoro-5-hydroxyphenyl)-3-oxo-2-(4-pyrazol-1-ylbenzyl)butyramideHCID 86642373—

Reaction Steps

The title compound was prepared by the method of Preparation 11b using 3-oxo-2-(4-pyrazol-1-ylbenzyl)thiobutyric acid S-tert-butyl ester and 3-amino-4-fluorophenol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08173812B2
Source datasetuspto-grants-2012_05
ORD IDord-a599f213fd3343be8b3220424b64302b
Source noteuspto-grants-2012_05