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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1922121Generated: October 26, 2026

(3-Amino-4-fluorophenoxy)acetic acid methyl ester → [8-Fluoro-2-isopropyl-4-oxo-3-(4-pyrazol-1-ylbenzyl)-1,4-dihydroquinolin-5-yloxy]acetic acid methyl ester

https://huagongshe.com/reaction/1922121

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3-Amino-4-fluorophenoxy)acetic acid methyl esterHCID 66717607—
Reactant4-Methyl-3-oxo-2-(4-pyrazol-1-ylbenzyl)pentanoic acid ethyl esterHCID 67457652—
Product[8-Fluoro-2-isopropyl-4-oxo-3-(4-pyrazol-1-ylbenzyl)-1,4-dihydroquinolin-5-yloxy]acetic acid methyl esterHCID 67459089—

Reaction Steps

The title compound was prepared by the method of Preparation 1c using (3-amino-4-fluorophenoxy)acetic acid methyl ester and 4-methyl-3-oxo-2-(4-pyrazol-1-ylbenzyl)pentanoic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08173812B2
Source datasetuspto-grants-2012_05
ORD IDord-8b2c83a4860c41cab89aac85816190b4
Source noteuspto-grants-2012_05