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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 192241Generated: October 25, 2026

1,2-Dichloroethane → 4-Amino-2-(4-chloro-2-fluoro-3-methoxyphenyl)-5-ethenyl-6-methoxycarbonylpyrimidine

https://huagongshe.com/reaction/192241

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantTributylvinyltinHCID 81998—
Reactant6-Amino-5-bromo-2-(4-chloro-2-fluoro-3-methoxyphenyl)-pyrimidine-4-carboxylic acid methyl esterHCID 59432116—
Product4-Amino-2-(4-chloro-2-fluoro-3-methoxyphenyl)-5-ethenyl-6-methoxycarbonylpyrimidineHCID 59432122—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-bfc2a980089749fc936d95553e8321e2
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)