1,2-Dichloroethane → 4-Amino-2-(4-chloro-2-fluoro-3-methoxyphenyl)-5-ethenyl-6-methoxycarbonylpyrimidine
Reaction equation
[CH2:23]([CH2:24][CH2:36][CH3:37])[Sn:25]([CH2:26][CH2:27][CH2:28][CH3:29])([CH2:30][CH2:31][CH2:32][CH3:33])[CH:34]=[CH2:35].[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7](-[c:13]2[c:14]([F:22])[c:15]([O:20][CH3:21])[c:16]([Cl:19])[cH:17][cH:18]2)[n:8][c:9]([NH2:12])[c:10]1[Br:11].[Cl:38][CH2:39][CH2:40][Cl:41].[Pd:42]([Cl:43])[Cl:44].[c:45]1([P:46]([c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)[c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)[cH:59][cH:60][cH:61][cH:62][cH:63]1.[c:64]1([P:65]([c:66]2[cH:67][cH:68][cH:69][cH:70][cH:71]2)[c:72]2[cH:73][cH:74][cH:75][cH:76][cH:77]2)[cH:78][cH:79][cH:80][cH:81][cH:82]1>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7](-[c:13]2[c:14]([F:22])[c:15]([O:20][CH3:21])[c:16]([Cl:19])[cH:17][cH:18]2)[n:8][c:9]([NH2:12])[c:10]1[CH:23]=[CH2:24]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-bfc2a980089749fc936d95553e8321e2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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