Acetic Acid → 4-[5-(Cyclopropyl-amino)-8,8-dimethyl-5,6,7,8-tetrahydro-naphthalene-2-yl-ethynyl]-2-fluoro-benzoic acid ethyl ester
Reaction equation
[C:35]([BH3-:36])#[N:37].[CH2:1]([CH3:2])[O:3][C:4]([c:5]1[c:6]([F:26])[cH:7][c:8]([C:11]#[C:12][c:13]2[cH:14][c:15]3[c:20]([cH:21][cH:22]2)[C:19](=[O:23])[CH2:18][CH2:17][C:16]3([CH3:24])[CH3:25])[cH:9][cH:10]1)=[O:27].[CH3:39][CH2:40][CH2:41][CH2:42][CH2:43][CH3:44].[CH3:45][CH2:46][O:47][C:48](=[O:49])[CH3:50].[CH3:51][C:52](=[O:53])[OH:54].[CH3:55][C:56]#[N:57].[CH:31]1([NH2:34])[CH2:32][CH2:33]1.[Cl:28][CH2:29][Cl:30].[Na+:38]>>[CH2:1]([CH3:2])[O:3][C:4]([c:5]1[c:6]([F:26])[cH:7][c:8]([C:11]#[C:12][c:13]2[cH:14][c:15]3[c:20]([cH:21][cH:22]2)[CH:19]([NH:34][CH:31]2[CH2:32][CH2:33]2)[CH2:18][CH2:17][C:16]3([CH3:24])[CH3:25])[cH:9][cH:10]1)=[O:27]Participants
10
Reactant 9
Product 1
Sources & evidence
- ORD record
- ord-73a50624b033412c973ac6fc33f08196
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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