反应详情

To a stirred solution of 2-(methyl(3-(6-nitro-3,4-dihydroquinolin-1(2H)-yl)propyl)amino)ethanol (76 mg, 0.259 mmol) in ethanol (2 mL) and tetrahydrofuran (2.0 mL) was added palladium, 10 wt % on activated carbon (27.6 mg, 0.026 mmol). The reaction mixture was stirred under an atmosphere of hydrogen (balloon pressure) for 2 h. The reaction mixture was then filtered through a pad of celite (washed with methanol) and concentrated to give a dark oil. The crude product was used directly in the subsequent reaction.

1. filtrationThe reaction mixture was then filtered through a pad of celite (washed with methanol)
2. concentrationconcentrated
3. customto give a dark oil