Dichloromethane → (1-{5-carbamoyl-4-[1-(2-chlorophenyl)-2,2,2-trifluoroethoxy]-2-thienyl}-1H-imidazo[4,5-c]pyridin-6-yl)methyl methanesulfonate

HRID 192271Notes

Reaction equation

HRID 192271 reaction equation
[CH3:33][S:34]([Cl:35])(=[O:36])=[O:37].[CH3:38][CH2:39][N:40]([CH2:41][CH3:42])[CH2:43][CH3:44].[Cl:1][c:2]1[c:3]([CH:8]([C:9]([F:10])([F:11])[F:12])[O:13][c:14]2[c:15]([C:30](=[O:31])[NH2:32])[s:16][c:17](-[n:19]3[cH:20][n:21][c:22]4[cH:23][n:24][c:25]([CH2:28][OH:29])[cH:26][c:27]34)[cH:18]2)[cH:4][cH:5][cH:6][cH:7]1.[Cl:45][CH2:46][Cl:47]>>[Cl:1][c:2]1[c:3]([CH:8]([C:9]([F:10])([F:11])[F:12])[O:13][c:14]2[c:15]([C:30](=[O:31])[NH2:32])[s:16][c:17](-[n:19]3[cH:20][n:21][c:22]4[cH:23][n:24][c:25]([CH2:28][O:29][S:34]([CH3:33])(=[O:36])=[O:37])[cH:26][c:27]34)[cH:18]2)[cH:4][cH:5][cH:6][cH:7]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 68766267HCID 68766267, compound

Product 1

HCID 86647108(1-{5-carbamoyl-4-[1-(2-chlorophenyl)-2,2,2-trifluoroethoxy]-2-thienyl}-1H-imidazo[4,5-c]pyridin-6-yl)methyl methanesulfonate

Sources & evidence

ORD record
ord-47d696e0439a47598b028688b60f5789
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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