Hydrochloric Acid → piperidin-4-yl 7-[2-amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-3,4-dihydroisoquinoline-2(1H)-carboxylate
Reaction equation
[CH2:42]1[O:43][CH2:44][CH2:45][O:46][CH2:47]1.[CH3:48][OH:49].[ClH:1].[NH2:2][c:3]1[n:4][c:5]([N:35]2[CH2:36][CH2:37][N:38]([CH3:41])[CH2:39][CH2:40]2)[cH:6][c:7](-[c:9]2[cH:10][cH:11][c:12]3[c:17]([cH:18]2)[CH2:16][N:15]([C:19](=[O:20])[O:21][CH:22]2[CH2:23][CH2:24][N:25]([C:28]([O:29][C:30]([CH3:31])([CH3:32])[CH3:33])=[O:34])[CH2:26][CH2:27]2)[CH2:14][CH2:13]3)[n:8]1>>[NH2:2][c:3]1[n:4][c:5]([N:35]2[CH2:36][CH2:37][N:38]([CH3:41])[CH2:39][CH2:40]2)[cH:6][c:7](-[c:9]2[cH:10][cH:11][c:12]3[c:17]([cH:18]2)[CH2:16][N:15]([C:19](=[O:20])[O:21][CH:22]2[CH2:23][CH2:24][NH:25][CH2:26][CH2:27]2)[CH2:14][CH2:13]3)[n:8]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-0cf8e5ccf1094e82864a2c907ae0ffca
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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