Dibenzylamine → HCID 59605251, compound

HRID 1923207Notes

Reaction equation

HRID 1923207 reaction equation
Cl[C:2]1[NH:6][C:5]2[CH:7]=[CH:8][CH:9]=[CH:10][C:4]=2[N:3]=1.[CH2:11]([NH:18][CH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[CH2:19]([N:18]([CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C:2]1[NH:6][C:5]2[CH:7]=[CH:8][CH:9]=[CH:10][C:4]=2[N:3]=1)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 7656DibenzylamineHCID 785722-Chlorobenzimidazole

Product 1

HCID 59605251HCID 59605251, compound

Conditions

Temperature
170 °C

Procedure

2-Chloro-1H-benzo[d]imidazole (1 g) was added to a neat solution of dibenzylamine (7 mL) and heated to 170° C. for 1.5 hours in a Biotage microwave synthesizer. The reaction mixture was concentrated to dryness and purified via flash column chromatography to afford 0.6 g of N,N-dibenzyl-1H-benzo[d]imidazol-2-amine.

Workup

  1. concentrationThe reaction mixture was concentrated to dryness
  2. custompurified via flash column chromatography

Sources & evidence

ORD record
ord-e7d67a46fdac4f8789e9ea3008d9f070
Source dataset
uspto-grants-2012_05
Patent number
US08173650B2

Reaction notes

Loading…