反应详情

温度

125 °C

A mixture of 0.8 g (5.36 mmol) of 5-hydroxy-1,2,3,4-tetrahydroquinoline and 0.5 g 1,3-propanesultone (4.1 mmol) in 12 ml of butyronitrile was heated at 125° C. for hours. The mixture was suction filtered and the filtrate evaporated under reduced pressure. The resulting off white compound crystallized. Product washed with ethyl ether and filtered of. Yield 0.8 g (80%)

1. filtrationfiltered
2. customthe filtrate evaporated under reduced pressure
3. customThe resulting off white compound crystallized
4. washProduct washed with ethyl ether
5. filtrationfiltered of