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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1923513Generated: October 29, 2026

4-Aminotetrahydropyran → HCID 49782490, compound

https://huagongshe.com/reaction/1923513

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-AminotetrahydropyranHCID 419223—
ReactantHCID 66643592HCID 66643592—
ProductHCID 49782490HCID 4978249046%

Reaction Steps

As described for example 22b, 2-[2-(5-methyl-3-pyridin-2-yl-isoxazol-4-yl)-ethyl]-thiazole-5-carboxylic acid (77 mg, 0.24 mmol) was converted, using 4-aminotetrahydropyran instead of isopropylamine, to the title compound (45 mg, 46%) which was obtained as a white solid MS: m/e=399.1 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08178522B2
Source datasetuspto-grants-2012_05
ORD IDord-43947c243f164505b513467f0eb0e82d
Source noteuspto-grants-2012_05