HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Thiophenamine, tetrahydro-, 1,1-dioxide → HCID 59568523, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Thiophenamine, tetrahydro-, 1,1-dioxide | HCID 22807 | — |
| Reactant | HCID 66643592 | HCID 66643592 | — |
| Product | HCID 59568523 | HCID 59568523 | 37% |
Reaction Steps
As described for example 22b, 2-[2-(5-methyl-3-pyridin-2-yl-isoxazol-4-yl)-ethyl]-thiazole-5-carboxylic acid (73 mg, 0.23 mmol) was converted, using 1,1-dioxidotetrahydrothien-3-ylamine instead of isopropylamine, to the title compound (37 mg, 37%) which was obtained as a brown solid MS: m/e=433.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178522B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-94a8bbe9b9ad4df1bc7b8761edcc07c0 |
| Source note | uspto-grants-2012_05 |