HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanamine, 2,2,2-trifluoro- → HCID 49783338, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanamine, 2,2,2-trifluoro- | HCID 9773 | — |
| Reactant | HCID 66643592 | HCID 66643592 | — |
| Product | HCID 49783338 | HCID 49783338 | 79% |
Reaction Steps
As described for example 22b, 2-[2-(5-methyl-3-pyridin-2-yl-isoxazol-4-yl)-ethyl]-thiazole-5-carboxylic acid (73 mg, 0.23 mmol) was converted, using 2,2,2-trifluoroethylamine instead of isopropylamine, to the title compound (72 mg, 79%) which was obtained as an off white solid MS: m/e=397.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178522B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-e9a9e326356b4beba027ec9adb7af2dc |
| Source note | uspto-grants-2012_05 |