HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Amino-2-propanol → HCID 49782273, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Amino-2-propanol | HCID 4 | — |
| Reactant | 2-[2-(3-Butyl-5-methyl-isoxazol-4-yl)-ethyl]-4-methyl-thiazole-5-carboxylic acid methyl ester | HCID 66643681 | — |
| Product | HCID 49782273 | HCID 49782273 | 49% |
Reaction Steps
As described for example 53, 2-[2-(3-butyl-5-methyl-isoxazol-4-yl)-ethyl]-4-methyl-thiazole-5-carboxylic acid methyl ester (100 mg, 0.31 mmol) was converted, using rac-1-amino-2-propanol instead of 2-amino-1,3-propandiol, to the title compound (65 mg, 49%) which was obtained as an off white oil. MS: m/e=366.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178522B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-5f11efda84b5494c974d0642dfd8c489 |
| Source note | uspto-grants-2012_05 |