反应详情

As described for example 53, 2-[2-(3-butyl-5-methyl-isoxazol-4-yl)-ethyl]-4-methyl-thiazole-5-carboxylic acid methyl ester (100 mg, 0.31 mmol) was converted, using rac-1-amino-2-propanol instead of 2-amino-1,3-propandiol, to the title compound (65 mg, 49%) which was obtained as an off white oil. MS: m/e=366.1 [M+H]+.