HCID 67521026, compound → HCID 67521558, compound

Participants

Reaction Steps

{2-Diethylamino-3-[2-(3,5-difluoro-phenyl)-acetylamino]-4-oxo-3,4-dihydro-quinazolin-6-yl}-carbamic acid tert-butyl ester was dissolved in 1 M HCl in acetic acid. The mixture was stirred at RT for 1 h. The mixture was evaporated to near dryness, followed by addition of diethyl ether. The formed precipitate was collected by filtration, washed with diethyl ether and dried to give the title compound as a hydrochloride salt (0.40 g, 77%).

Provenance & Evidence