o-(Trifluoromethyl)benzaldehyde → HCID 59532609, compound

Participants

Reaction Conditions

Reaction Steps

2-(Trifluoromethyl)benzaldehyde (4-B) (135 μL, 1.0 mmol) was added to a partial solution of 2-naphthohydrazide (4-A) (186 mg, 1.0 mmol) in ethanol (4 mL) at 70° C. and the mixture stirred at 70° C. for 2 h. The mixture was cooled and the thick precipitate was filtered, washed with cold ethanol and dried to give N′-{(1E)-[2-(trifluoromethyl)phenyl]-methylene}-2-naphthohydrazide (4-C).

Provenance & Evidence