HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-Phenyl-3-(2-o-tolyl-2H-pyrazol-3-yl)-1H-pyridazin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | o-Tolylhydrazine | HCID 68256 | — |
| Reactant | (E)-3-(3-(Dimethylamino)acryloyl)-1-phenylpyridazin-4(1H)-one | HCID 12742246 | — |
| Product | 1-Phenyl-3-(2-o-tolyl-2H-pyrazol-3-yl)-1H-pyridazin-4-one | HCID 46219192 | 55% |
Reaction Steps
The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-phenyl-1H-pyridazin-4-one (A-1) and o-tolylhydrazine×HCl according to the method described for Example 1 in 55% yield. MS: M=329.1 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178538B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-9dc8f760076147159d08dedf0c1403e4 |
| Source note | uspto-grants-2012_05 |