HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-(Trifluoromethyl)phenyl)hydrazine → 1-Phenyl-3-[2-(3-trifluoromethyl-phenyl)-2H-pyrazol-3-yl]-1H-pyridazin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-(Trifluoromethyl)phenyl)hydrazine | HCID 98650 | — |
| Reactant | (E)-3-(3-(Dimethylamino)acryloyl)-1-phenylpyridazin-4(1H)-one | HCID 12742246 | — |
| Product | 1-Phenyl-3-[2-(3-trifluoromethyl-phenyl)-2H-pyrazol-3-yl]-1H-pyridazin-4-one | HCID 46219193 | 58% |
Reaction Steps
The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-phenyl-1H-pyridazin-4-one (A-1) and 3-(trifluoromethyl)-phenylhydrazine according to the method described for Example 1 in 58% yield. MS: M=383.0 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178538B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-cc2d1d4274fe4e11a9f7772eb13e2519 |
| Source note | uspto-grants-2012_05 |